The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2012
Filed:
Oct. 02, 2007
Stefan Golz, Essen, DE;
Holger Summer, Wuppertal, DE;
Andreas Geerts, Wuppertal, DE;
Ulf Brüggemeier, Leichlingen, DE;
Barbara Albrecht-küpper, Wülfrath, DE;
Martina Klein, Düsseldorf, DE;
Sonja Steppan, Neu-Isenburg, DE;
Peter Ellinghaus, Melle, DE;
Donatella D'urso, Düsseldorf, DE;
Michael Seewald, Berlin, DE;
Hendrik Milting, Bad Oeynhausen, DE;
Stefan Golz, Essen, DE;
Holger Summer, Wuppertal, DE;
Andreas Geerts, Wuppertal, DE;
Ulf Brüggemeier, Leichlingen, DE;
Barbara Albrecht-Küpper, Wülfrath, DE;
Martina Klein, Düsseldorf, DE;
Sonja Steppan, Neu-Isenburg, DE;
Peter Ellinghaus, Melle, DE;
Donatella D'Urso, Düsseldorf, DE;
Michael Seewald, Berlin, DE;
Hendrik Milting, Bad Oeynhausen, DE;
Bayer Schering Pharma Aktiengesellschaft, Berlin, DE;
Abstract
The invention provides LTBP2, which is associated with cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of LTBP2 as well as pharmaceutical compositions comprising such compounds. The invention also provides LTBP2 as a biomarker for diseases such as cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases.