The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2012
Filed:
May. 15, 2008
Applicants:
Yu-shen Hsu, Xizhi, TW;
Young-sun Lin, Xizhi, TW;
Ta-tung Yuan, San Marino, CA (US);
Inventors:
Assignee:
Development Center for Biotechnology, Xizhi, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/108 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to a mutantheat-labile enterotoxin (LT) subunit A that can be used as an adjuvant. This subunit A mutant contains an amino acid substitution at a position corresponding to position 61 of a wild-type LT. An LT containing this mutated subunit A exhibits reduced toxicity compared to its wild type counterpart.