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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8086412 B1

PDFFull Text
Expired
Date of Patent:
Dec. 27, 2011

Filed:

Jun. 19, 2009

Corrective methodology for processing results of transcriptome experiments obtained by differential analysis

Applicants:

Paul Fogel, Paris, FR;

Didier Zugaj, Nateau sur Essonne, FR;

Jean-marc Le Goff, Marseilles, FR;

Jérôme Aubert, Grasse, FR;

Sophie Deret, Mougins, FR;

Inventors:

Paul Fogel, Paris, FR;

Didier Zugaj, Nateau sur Essonne, FR;

Jean-Marc Le Goff, Marseilles, FR;

Jérôme Aubert, Grasse, FR;

Sophie Deret, Mougins, FR;

Assignee:

Galderma Research & Development, Biot, FR;

Attorney:

Buchanan Ingersoll & Rooney, P.C.

Primary Examiner:

John H Le

Int. Cl.
CPC ...
G01N 33/48 (2006.01); G06F 19/00 (2011.01);
U.S. Cl.
CPC ...
Abstract

A corrective method is described for processing results of transcriptome experiments obtained by differential analysis includes the following steps: obtaining the results of the level of expression of genes under a reference condition, and calculating the mean level of expression of each of such genes; obtaining the results of the level of expression of such genes under a treatment condition, and calculating the mean level of expression for each of such genes; calculating the modulation coefficient for the level of expression for each of such genes; calculating a p-value associated with each modulation coefficient; and calculating isobar curves of p-value as a function of the mean level of expression of each of such genes under the reference condition; calculating and associating a median modulation coefficient on the isobar curve of each p-value observed. The processing of results of experiments carried out on DNA chips is also described.

Find Patent Forward Citations

Fogel, Paul. (2011). Corrective methodology for processing results of transcriptome experiments obtained by differential analysis (U.S. Patent No. 8086412). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8086412

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