The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2011
Filed:
Mar. 20, 2007
Amit Joshi, Houston, TX (US);
Eva Sevick-muraca, Montgomery, TX (US);
Amit Joshi, Houston, TX (US);
Eva Sevick-Muraca, Montgomery, TX (US);
Baylor College of Medicine, Houston, TX (US);
Abstract
A method and system for non-contact fluorescent optical tomography using patterned illumination is disclosed. The method comprises illuminating a surface of a medium with light from at least one excitation light source to project at least two patterns. Each pattern comprises at least one motif, wherein the medium comprises at least one fluorescent target. The method further comprises for each pattern, measuring excitation light reflected from the medium to generate an excitation data set. In addition, the method comprises, for each pattern, measuring fluorescence emitted from the at least one fluorescent target to generate a fluorescence data set. The method also comprises generating a 3D image of the at least one fluorescent target in the medium by applying iterative algorithm. The iterative algorithm minimizes the difference between a predicted data set based on a mathematical model, and each excitation data set and each fluorescence data set.