The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2011
Filed:
Mar. 16, 2009
Raffaella Volpicelli, Vicenza, IT;
Paolo Maragni, Virgilio, IT;
Franco Massaccesi, Grancona, IT;
Ilaria Munari, Vicenza, IT;
Livius Cotarca, Cervignano del Friuli, IT;
Johnny Foletto, Arcole, IT;
Raffaella Volpicelli, Vicenza, IT;
Paolo Maragni, Virgilio, IT;
Franco Massaccesi, Grancona, IT;
Ilaria Munari, Vicenza, IT;
Livius Cotarca, Cervignano del Friuli, IT;
Johnny Foletto, Arcole, IT;
Zach System S.p.A., Bresso (MI), IT;
Abstract
The present invention relates to a process for reducing a compound of formula (I) wherein X is halogen, a hydroxy group, an alkylsulfoniloxy group or an arylsulfonyloxy group; to give a compound of formula (II) as a diastereoisomerically pure compound of RS/SR configuration characterized in that said reduction is carried out by the use of (+)-B-chlorodiisopinocampheylborane or (−)-B-chlorodiisopinocampheylborane. The compounds of formula (II) are useful as intermediates for the preparation of Nebivolol.