The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2011
Filed:
Aug. 29, 2008
Alexei Bogdanov, Westborough, MA (US);
Valeriy Metelev, Moscow, RU;
David Tabatadze, Worcester, MA (US);
Paul Zamecnik, Boston, MA (US);
Alexei Bogdanov, Westborough, MA (US);
Valeriy Metelev, Moscow, RU;
David Tabatadze, Worcester, MA (US);
Paul Zamecnik, Boston, MA (US);
University of Massachusetts, Shrewsbury, MA (US);
The General Hospital Corporation Massachusetts, Boston, MA (US);
Abstract
Described are phosphoramidite nucleoside analog monomers, precursors thereof, and oligonucleotides including one or more of the monomers. The monomers can be used during automated synthesis of oligonucleotide derivatives, and allow for incorporation of one or several reporter groups, organic molecules, bio-molecules, small molecules or other chemical groups at the internucleoside phosphotriesters. Oligonucleotides including the monomers have a number of uses in therapeutic, diagnostic, and research applications.