The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2011
Filed:
Sep. 15, 2004
Axel Choidas, Gauting, DE;
Alexander Backes, Munich, DE;
Matt Cotten, Barjul, GM;
Ola Engkvist, Bjärnum, SE;
Beatrice Felber, Eching, DE;
Achim Freisleben, Munich, DE;
Klaus Godl, Krailling, DE;
Zoltán Greff, Budapest, HU;
Peter Habenberger, Munich, DE;
Doris Hafenbradl, Pullach, DE;
Christian Hartung, Munich, DE;
Thomas Herget, Darmstadt, DE;
Edmund Hoppe, Krailling, DE;
Bert Klebl, Oberschweinbad, DE;
Andrea Missio, Sovizzo, IT;
Gerhard Müller, Utting, DE;
Wilfried Schwab, Neuried, DE;
Birgit Zech, Gräfelfing, DE;
Jose Bravo, Haverhill, GB;
John Harris, Eynsford, GB;
Joelle Le, London, GB;
Jackie Macritchie, Walden, GB;
Vladimir Savic, Belgrade, RS;
Brad Sherborne, Auchterarder, GB;
Don Simpson, Haverhill, GB;
Axel Choidas, Gauting, DE;
Alexander Backes, Munich, DE;
Matt Cotten, Barjul, GM;
Ola Engkvist, Bjärnum, SE;
Beatrice Felber, Eching, DE;
Achim Freisleben, Munich, DE;
Klaus Godl, Krailling, DE;
Zoltán Greff, Budapest, HU;
Peter Habenberger, Munich, DE;
Doris Hafenbradl, Pullach, DE;
Christian Hartung, Munich, DE;
Thomas Herget, Darmstadt, DE;
Edmund Hoppe, Krailling, DE;
Bert Klebl, Oberschweinbad, DE;
Andrea Missio, Sovizzo, IT;
Gerhard Müller, Utting, DE;
Wilfried Schwab, Neuried, DE;
Birgit Zech, Gräfelfing, DE;
Jose Bravo, Haverhill, GB;
John Harris, Eynsford, GB;
Joelle Le, London, GB;
Jackie Macritchie, Walden, GB;
Vladimir Savic, Belgrade, RS;
Brad Sherborne, Auchterarder, GB;
Don Simpson, Haverhill, GB;
Lead Discovery Center GmbH, Dortmund, DE;
Bayer Pharma AG, Berlin, DE;
Abstract
The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said 4,6-disubstituted aminopyrimidine derivatives as inhibitors for a protein kinase and a medium comprising at least one of said 4,6-disubstituted aminopyrimidine derivatives in an immobilized form and the use of said medium for enriching, purifying and/or depleting nucleotide binding proteins which bind to the immobilized 4,6-disubstituted aminopyrimidine derivatives.