The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8084415 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 27, 2011

Filed:

Nov. 01, 2007
Applicants:

Anil B. Mukherjee, Brookeville, MD (US);

Feng Zheng, Rockville, MD (US);

Zhongjian Zhang, Rockville, MD (US);

Inventors:

Anil B. Mukherjee, Brookeville, MD (US);

Feng Zheng, Rockville, MD (US);

Zhongjian Zhang, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
Abstract

Uteroglobin has been discovered to prevent IgA mediated diseases, such as IgA nephropathy, by preventing the deposition of IgA-Fibronectin immunocomplexes in tissues such as the renal glomeruli. The invention therefore includes methods of treating such diseases by administering therapeutically effective amounts of uteroglobin (and variants or mimetics) to prevent or improve the IgA mediated condition. Transgenic uteroglobin knockout animals, and animals in which uteroglobin-protein expression is reduced by antisense technology, also provide systems for studying IgA mediated diseases, and screening for appropriate treatments.


Find Patent Forward Citations

Mukherjee, Anil. (2011). Uteroglobin in the treatment of iga mediated nephropathy (U.S. Patent No. 8084415). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8084415

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