The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8084209 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 27, 2011

Filed:

Jul. 21, 2006
Applicants:

Marisa Lin Wong Medina, Hercules, CA (US);

Ronald M. Krauss, Berkeley, CA (US);

Inventors:

Marisa Lin Wong Medina, Hercules, CA (US);

Ronald M. Krauss, Berkeley, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for assessing a subject's responsiveness to a HMGCR inhibitor therapy, and selection of a HMGCR inhibitor therapy based upon such methods. The invention further provides methods for identifying agents that modulate HMGCR activity, e.g., through modulating HMGCR mRNA splicing, while avoiding elevation of the statin-resistant isoform of HMGCR.


Find Patent Forward Citations

Medina, Marisa Lin Wong. (2011). Hmgcr isoforms in prediction of efficacy and identification of cholesterol-modulating compounds (U.S. Patent No. 8084209). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8084209

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