The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2011

Filed:

Jan. 23, 2004
Applicants:

William R. Jacobs, Jr., Pelham, NY (US);

Tsungda Hsu, Bronx, NY (US);

Vasan Sambandamurthy, Singapore, SG;

Sheldon Morris, Beltsville, MD (US);

Stoyan Bardarov, Worcester, MA (US);

Svetoslav Bardarov, Legal Representative, Worcester, MA (US);

Inventors:

William R. Jacobs, Jr., Pelham, NY (US);

Tsungda Hsu, Bronx, NY (US);

Vasan Sambandamurthy, Singapore, SG;

Sheldon Morris, Beltsville, MD (US);

Stoyan Bardarov, Worcester, MA (US);

Svetoslav Bardarov, legal representative, Worcester, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); A61K 39/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of treating a mammal that is deficient in CD4and/or CD8lymphocytes are provided. The methods comprise inoculating the mammal with an attenuated mycobacterium in thecomplex. In these methods, the mycobacterium comprises two deletions, wherein a virulent mycobacterium in thecomplex having either deletion exhibits attenuated virulence. Use of these mycobacteria for the manufacture of a medicament for the treatment of mammals deficient in CD4and/or CD8lymphocytes is also provided.


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