The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2011
Filed:
Oct. 03, 2008
Jie Fei Cheng, San Diego, CA (US);
MI Chen, San Diego, CA (US);
Thomas Arrhenius, Del Mar, CA (US);
Mark E. Wilson, Ramona, CA (US);
Gary D. Lopaschuk, Edmonton, CA;
Jason R. Dyck, Sherwood Park, CA;
Rossy Serafimov, Las Vegas, NV (US);
Jie Fei Cheng, San Diego, CA (US);
Mi Chen, San Diego, CA (US);
Thomas Arrhenius, Del Mar, CA (US);
Mark E. Wilson, Ramona, CA (US);
Gary D. Lopaschuk, Edmonton, CA;
Jason R. Dyck, Sherwood Park, CA;
Rossy Serafimov, Las Vegas, NV (US);
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.