The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2011
Filed:
Oct. 24, 2005
Hang-cheol Shin, Seoul, KR;
Yean-hee Park, Seoul, KR;
Hyang-do Song, Gyeongsangnam-do, KR;
Eung-yoon Kim, Seoul, KR;
Ha-a-rin Chon, Jeollanam-do, KR;
Hye-ran Hyun, Seoul, KR;
Hang-Cheol Shin, Seoul, KR;
Yean-Hee Park, Seoul, KR;
Hyang-Do Song, Gyeongsangnam-do, KR;
Eung-Yoon Kim, Seoul, KR;
Ha-A-Rin Chon, Jeollanam-do, KR;
Hye-Ran Hyun, Seoul, KR;
Vexxon, Inc., Seoul, KR;
Abstract
The present invention relates to a method for producing a recombinant protein capable of increasing expression rate of a target protein and also improving solubility and folding of the expressed target protein using a modified protein disulfide isomerase (PDI) as a fusion partner, and an expression vector containing the modified PDI gene as a fusion partner. The method for preparing a recombinant protein using a modified PDI as a fusion partner according to the present invention may solve the problems concerning a low yield and solubility and folding that conventional fusion partners have, and be widely used for protein drug and industrial protein production.