The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2011
Filed:
Dec. 11, 2007
Solomon H. Snyder, Baltimore, MD (US);
Anutosh Chakraborty, Baltimore, MD (US);
Michael Koldobskiy, Baltimore, MD (US);
Katherine Sixt, Baltimore, MD (US);
Krishna Juluri, Baltimore, MD (US);
Asif K Mustafa, Baltimore, MD (US);
Damian B Van Rossum, University Park, PA (US);
Randen L Patterson, University Park, PA (US);
Solomon H. Snyder, Baltimore, MD (US);
Anutosh Chakraborty, Baltimore, MD (US);
Michael Koldobskiy, Baltimore, MD (US);
Katherine Sixt, Baltimore, MD (US);
Krishna Juluri, Baltimore, MD (US);
Asif K Mustafa, Baltimore, MD (US);
Damian B Van Rossum, University Park, PA (US);
Randen L Patterson, University Park, PA (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
Anti-cancer drugs are identified by screening for agents and compounds which inhibit the binding of HSP90 and IP6K2. In vitro and in vivo assays can be used. Any phenomenon associated with the binding or inhibition can be monitored, including cell death, subcellular localization, catalytic activity of IP6K2, and IP7 formation.