The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2011
Filed:
Oct. 21, 2005
Applicants:
Craig M. Meyers, Hummelstown, PA (US);
Samina Alam, Hershey, PA (US);
Inventors:
Craig M. Meyers, Hummelstown, PA (US);
Samina Alam, Hershey, PA (US);
Assignee:
The Penn State Research Foundation, University Park, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); C12N 15/37 (2006.01);
U.S. Cl.
CPC ...
Abstract
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same.