The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2011

Filed:

May. 18, 2007
Applicants:

Der-shing Huang, Folsom, CA (US);

Olivier Dapremont, Citrus Heights, CA (US);

Patrick Berget, Sacramento, CA (US);

Xa Her, Rancho Cordova, CA (US);

Darin Sanchez, Folsom, CA (US);

Inventors:

Der-Shing Huang, Folsom, CA (US);

Olivier Dapremont, Citrus Heights, CA (US);

Patrick Berget, Sacramento, CA (US);

Xa Her, Rancho Cordova, CA (US);

Darin Sanchez, Folsom, CA (US);

Assignee:

Ampac Fine Chemicals LLC., Rancho Cordova, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 51/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

High yields and purity are obtained in the purification of enantiomers of chiral carboxylic acids by preparative-scale chromatography by including a tertiary alcohol in the mobile phase in conjunction with an acidic modifier and a hydrophobic solvent. The tertiary alcohol is superior to other, more commonly used alcohols by reducing the extent of esterification of the enantiomer that otherwise lowers the yield and the purity.


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