The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2011

Filed:

Apr. 18, 2007
Applicants:

Andreas Goutopoulos, Boston, MA (US);

Benny C. Askew, Jr., Marshfield, MA (US);

Xiaoling Chen, Newton, MA (US);

Srinivasa Karra, Pembroke, MA (US);

Henry Yu, Wellesley, MA (US);

Inventors:

Andreas Goutopoulos, Boston, MA (US);

Benny C. Askew, Jr., Marshfield, MA (US);

Xiaoling Chen, Newton, MA (US);

Srinivasa Karra, Pembroke, MA (US);

Henry Yu, Wellesley, MA (US);

Assignee:

Merck Serono S.A., Coinsins, Vaud, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/00 (2006.01); C07D 413/04 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides novel heteroaryl-substituted arylaminopyridine derivative MEK inhibitors of Formula (Ia) Such compounds are MEK inhibitors that are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation. Also disclosed is the treatment of a hyperproliferative disease in mammals, and pharmaceutical compositions containing such compounds.


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