The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2011

Filed:

Mar. 29, 2010
Applicants:

LI Chen, Shanghai, CN;

Xingchun Han, Shanghai, CN;

Song Yang, Shanghai, CN;

Zhuming Zhang, Hillsborough, NJ (US);

Inventors:

Li Chen, Shanghai, CN;

Xingchun Han, Shanghai, CN;

Song Yang, Shanghai, CN;

Zhuming Zhang, Hillsborough, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided compounds of the formula or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W', V, V′, V″, R, Rand Rare as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.


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