The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
Apr. 08, 2005
Tomohiro Chiba, Tokyo, JP;
Yoshiko Kita, Tokyo, JP;
Masaaki Matsuoka, Tokyo, JP;
Kenzo Terashita, Tokyo, JP;
Sadakazu Aiso, Tokyo, JP;
Ikuo Nishimoto, Chiba, JP;
Tomo Nishimoto, Legal Representative, Chiba, JP;
Tomohiro Chiba, Tokyo, JP;
Yoshiko Kita, Tokyo, JP;
Masaaki Matsuoka, Tokyo, JP;
Kenzo Terashita, Tokyo, JP;
Sadakazu Aiso, Tokyo, JP;
Ikuo Nishimoto, Chiba, JP;
Tomo Nishimoto, legal representative, Chiba, JP;
Tomohiro Chiba, Tokyo, JP;
Massaaki Matsuoka, Tokyo, JP;
Kenzo Terashita, Tokyo, JP;
Sadakazu Also, Tokyo, JP;
Tomo Nishimoto, Ichikawa-shi, JP;
Abstract
The present invention relates to a pharmaceutical composition for the treatment and/or prevention of a neurodegenerative disease, comprising the following polypeptide shown in any of (a) to (c): (a) a polypeptide comprising the amino acid sequence represented by Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1); (b) a polypeptide comprising an amino acid sequence having a deletion, substitution, insertion, and/or addition of one or several amino acids in the amino acid sequence consisting of Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro (SEQ ID NO: 1), and having an activity that inhibits neuronal cell death associated with neurodegenerative disease; and (c) a modified polypeptide from the polypeptide (a) or (b), or a pharmaceutically acceptable salt thereof, as an effective ingredient.