The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8076358 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 13, 2011

Filed:

Jan. 27, 2009
Applicants:

Ellen Baxter, Glenside, PA (US);

Christopher J. Creighton, San Diego, CA (US);

Tianbao LU, Churchville, PA (US);

Allen B. Reitz, Lansdale, PA (US);

Charles H. Reynolds, Lansdale, PA (US);

Tina Morgan Ross, Royerford, PA (US);

Ellen Sieber-mcmaster, Langhorne, PA (US);

Inventors:

Ellen Baxter, Glenside, PA (US);

Christopher J. Creighton, San Diego, CA (US);

Tianbao Lu, Churchville, PA (US);

Allen B. Reitz, Lansdale, PA (US);

Charles H. Reynolds, Lansdale, PA (US);

Tina Morgan Ross, Royerford, PA (US);

Ellen Sieber-McMaster, Langhorne, PA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61P 25/28 (2006.01); C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to 6-substituted-thio-2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of β-secretase, also known as β-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.


Find Patent Forward Citations

Baxter, Ellen. (2011). 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of β-secretase (bace) (U.S. Patent No. 8076358). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8076358

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