The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
Apr. 12, 2007
Brett P. Monia, Encinitas, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
William A. Gaarde, Carlsbad, CA (US);
Trisha Lockhart, Cardiff by the Sea, CA (US);
Robert Mckay, Poway, CA (US);
Brett P. Monia, Encinitas, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
William A. Gaarde, Carlsbad, CA (US);
Trisha Lockhart, Cardiff by the Sea, CA (US);
Robert McKay, Poway, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Disclosed herein are compounds, compositions and methods for modulating the expression of hepcidin in a cell, tissue or animal or preventing, ameliorating or treating anemia. Also provided are methods for prevention, amelioration or treatment of anemia, and for increasing red blood cell count in an animal. Also provided are methods for the prevention, amelioration and/or treatment of low serum iron levels, low red blood cell count and other clinical endpoints of anemia in an animal. These methods may be achieved by administration of compounds or compositions including antisense compounds targeted to a nucleic acid that expresses hepcidin polypeptide combined with an erythropoiesis stimulating agent.