The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
Dec. 10, 2003
Applicants:
Jonathan S. Stamler, Chapel Hill, NC (US);
David J. Singel, Bozeman, MT (US);
Inventors:
Jonathan S. Stamler, Chapel Hill, NC (US);
David J. Singel, Bozeman, MT (US);
Assignees:
Montana State University-Bozeman, Bozeman, MT (US);
Duke University, Durham, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
A01N 59/00 (2006.01); A61K 38/41 (2006.01); A61K 38/00 (2006.01); A61K 38/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
Contrary to current opinion that nitrite in general oxidizes hemoglobin with elimination of active nitric oxide, deoxygenated hemoglobin reacts with low concentration inorganic nitrite to produce very stable iron nitrosyl hemoglobin which on delivery into the body is converted to a hemoglobin capable of nitric oxide delivery and provides vasodilator and antiplatelet activity. This provides basis for ameliorated risk blood product transfusions.