The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
Jul. 19, 2004
Larry Brown, Newton, MA (US);
John K. Mcgeehan, Woodbury, NJ (US);
Julia Rashba-step, Newton, MA (US);
Terrence L. Scott, Winchester, MA (US);
Larry Brown, Newton, MA (US);
John K. McGeehan, Woodbury, NJ (US);
Julia Rashba-Step, Newton, MA (US);
Terrence L. Scott, Winchester, MA (US);
Baxter International Inc., Deerfield, IL (US);
Baxter Healthcare S.A., Wallisellen, CH;
Abstract
The present invention is related to a method for preparing small spherical particles of an active agent by providing a solution in a single liquid phase. The single liquid phase comprises an active agent, a phase separation enhancing agent, and a first solvent. A phase change is induced at a controlled rate in the solution to cause a liquid-solid phase separation of the active agent and to form a solid phase and a liquid phase. The solid phase comprises solid small spherical particles of the active agent. The liquid phase comprises the phase separation enhancing agent and the solvent. The small spherical particles are substantially spherical and having a size from about 0.01 μm to about 200 μm.