The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2011
Filed:
May. 22, 2009
Ron L. Hale, Sandia Park, NM (US);
Craig C. Hodges, Walnut Creek, CA (US);
Peter M. Lloyd, Walnut Creek, CA (US);
Daniel Mufson, Napa, CA (US);
Daniel D. Rogers, Oakland, CA (US);
Soonho Song, Hillsborough, CA (US);
Martin J. Wensley, Los Gatos, CA (US);
Daniel J. Myers, Mountain View, CA (US);
Jeffrey A. Mckinney, Lafayette, CA (US);
Reynaldo J. Quintana, Redwood City, CA (US);
Joshua D. Rabinowitz, Princeton, NJ (US);
Ron L. Hale, Sandia Park, NM (US);
Craig C. Hodges, Walnut Creek, CA (US);
Peter M. Lloyd, Walnut Creek, CA (US);
Daniel Mufson, Napa, CA (US);
Daniel D. Rogers, Oakland, CA (US);
Soonho Song, Hillsborough, CA (US);
Martin J. Wensley, Los Gatos, CA (US);
Daniel J. Myers, Mountain View, CA (US);
Jeffrey A. McKinney, Lafayette, CA (US);
Reynaldo J. Quintana, Redwood City, CA (US);
Joshua D. Rabinowitz, Princeton, NJ (US);
Alexza Pharmaceuticals, Inc., Mountain View, CA (US);
Abstract
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.