The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2011
Filed:
Jan. 08, 2008
Uday Rajaram Bapat, Mumbai, IN;
Munusamy Jayamani, Chennai, IN;
Sivaji Ravisaravanan, Madurai, IN;
Vigneshwara Ravisankar, Tirunelveli, IN;
Uday Rajaram Bapat, Mumbai, IN;
Munusamy Jayamani, Chennai, IN;
Sivaji Ravisaravanan, Madurai, IN;
Vigneshwara Ravisankar, Tirunelveli, IN;
Actavis Group PTC EHF, , IS;
Abstract
Described herein is an improved, commercially viable and industrially advantageous process for the preparation of paliperidone intermediate 9-hydroxy-3-(2-chloroethyl)-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one and its hydrochloride salt. The process provides the paliperidone intermediate in higher yield and reduced reaction time compared to the previously disclosed processes, thereby providing for production of paliperidone and its pharmaceutically acceptable acid addition salts in high purity and in high yield.