The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2011
Filed:
May. 30, 2007
David S. F. Young, Toronto, CA;
Helen P. Findlay, Toronto, CA;
Susan E. Hahn, Toronto, CA;
Lisa M. Cechetto, Seoul, KR;
Fortunata Mcconkey, Ontario, CA;
Maximiliano Vasquez, Palo Alto, CA (US);
David S. F. Young, Toronto, CA;
Helen P. Findlay, Toronto, CA;
Susan E. Hahn, Toronto, CA;
Lisa M. Cechetto, Seoul, KR;
Fortunata McConkey, Ontario, CA;
Maximiliano Vasquez, Palo Alto, CA (US);
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
This invention relates to the staging, diagnosis and treatment of cancerous diseases (both primary tumors and tumor metastases), particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more CDMAB/chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays, which utilize the CDMAB of the instant invention. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells.