The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2011
Filed:
Apr. 20, 2004
Swee Hin Teoh, Singapore, SG;
Dietmar Werner Hutmacher, Singapore, SG;
Kim Cheng Tan, Singapore, SG;
Kock Fye Tam, Singapore, SG;
Iwan Zein, Singapore, SG;
Swee Hin Teoh, Singapore, SG;
Dietmar Werner Hutmacher, Singapore, SG;
Kim Cheng Tan, Singapore, SG;
Kock Fye Tam, Singapore, SG;
Iwan Zein, Singapore, SG;
Osteopore International Pte. Ltd., Singapore, SG;
Abstract
The invention relates to the use of Fused Deposition Modeling to construct three-dimensional (3D) bioresorbable scaffolds from bioresorbable polymers such as polycaprolactone (PCL), or from composites of bioresorbable polymers and ceramics, such as polycaprolactone/hydroxyapatite (PCL/HA). Incorporation of a bioresorbable ceramic to produce a hybrid/composite material support provides the desired degradation and resorption kinetics. Such a composite material improves the biocompatibility and hard tissue integration and allows for increased initial flash spread of serum proteins. The basic resorption products of the composite also avoids the formation of an unfavorable environment for hard tissue cells due to a decreased pH. The scaffolds have applications in tissue engineering, e.g., in tissue engineering bone and cartilage.