The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 06, 2011
Filed:
Jan. 25, 2010
Jan Bergstrom, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-lennart Johansson, Uppsala, SE;
Anders Ljunglof, Uppsala, SE;
Jean-luc Maloisel, Uppsala, SE;
Jan Bergstrom, Uppsala, SE;
Gunnar Glad, Uppsala, SE;
Bo-Lennart Johansson, Uppsala, SE;
Anders Ljunglof, Uppsala, SE;
Jean-Luc Maloisel, Uppsala, SE;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Abstract
The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embodiment, the chemical gradient is a ligand density gradient. The invention also relates to a method of providing a separation matrix comprising ligands coupled to the surfaces of a porous support, in which method at least one ligand density gradient is provided by solvent-controlled diffusion of at least one reagent into the porous support.