The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
Jun. 12, 2009
Paul Charifson, Framingham, MA (US);
David Deininger, Waltham, MA (US);
Anne-laure Grillot, Somerville, MA (US);
Yusheng Liao, Lexington, MA (US);
Steven Ronkin, Watertown, MA (US);
Dean Stamos, Carlsbad, CA (US);
Emanuele Perola, Brookline, MA (US);
Tiansheng Wang, Concord, MA (US);
Arnaud Letiran, Lexington, MA (US);
Joseph Drumm, Westborough, MA (US);
Paul Charifson, Framingham, MA (US);
David Deininger, Waltham, MA (US);
Anne-Laure Grillot, Somerville, MA (US);
Yusheng Liao, Lexington, MA (US);
Steven Ronkin, Watertown, MA (US);
Dean Stamos, Carlsbad, CA (US);
Emanuele Perola, Brookline, MA (US);
Tiansheng Wang, Concord, MA (US);
Arnaud LeTiran, Lexington, MA (US);
Joseph Drumm, Westborough, MA (US);
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
The present invention relates to methods of treating, preventing, or lessening the severity of resistant bacterial infections in mammals, utilizing compounds of formula I or formula VII or pharmaceutically salts thereof. The present invention also relates to methods of using compounds of formula I or formula VII in combination with one or more additional antibacterial agents and/or one or more additional therapeutic agents that increase the susceptibility of bacterial organisms to antibiotics.