The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2011

Filed:

Dec. 04, 2009
Applicants:

Ashutosh S. Jogalekar, Decatur, GA (US);

James P. Snyder, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

Anthony G. M. Barrett, London, GB;

Raoul Charles Dalmedo Stuart Coombes, London, GB;

Simak Ali, London, GB;

Aleksandra Siwicka, Warsaw, PL;

Jan Brackow, Suhr, CH;

Bodo Scheiper, Frankfurt am Main, DE;

Inventors:

Ashutosh S. Jogalekar, Decatur, GA (US);

James P. Snyder, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

Anthony G. M. Barrett, London, GB;

Raoul Charles Dalmedo Stuart Coombes, London, GB;

Simak Ali, London, GB;

Aleksandra Siwicka, Warsaw, PL;

Jan Brackow, Suhr, CH;

Bodo Scheiper, Frankfurt am Main, DE;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2006.01); A01N 43/90 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a class of compounds which are useful for specifically inhibiting cyclin-dependent kinases. This class of compounds finds use in treating diseases resulting from inappropriate activity of cyclin-dependent kinases, including cancer, viral infections (e.g., HIV) neurodegenerative disorders (e.g. Alzheimer's disease), and cardiovascular disorders (e.g. atherosclerosis). Moreover, certain members of this class are particularly useful for inhibiting cyclin-dependent kinase 7 and are especially useful for the treatment of breast cancer.


Find Patent Forward Citations

Loading…