The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
Aug. 10, 2007
Nicolas Winssinger, Strasbourg, FR;
Sofia Barluenga, Strasbourg, FR;
Martin Karplus, Cambridge, MA (US);
Nicolas Winssinger, Strasbourg, FR;
Sofia Barluenga, Strasbourg, FR;
Martin Karplus, Cambridge, MA (US);
Universite de Strasbourg, Strasbourg, FR;
Le Centre National de la Recherche Scientifique, Paris Cedex, FR;
Abstract
Disclosed are macrocyclic compounds of formulae I-V, which are analogs of the pochonin resorcylic acid lactones, and processes for the preparation of the compounds. The compounds disclosed are useful as inhibitors of kinases and Heat Shock Protein 90 (HSP 90). Also disclosed are pharmaceutical compositions comprising an effective kinase-inhibiting amount or an effective HSP90-inhibiting amount of the compounds and methods for the treatment of disorders that are mediated by kinases and HSP90.