The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2011

Filed:

Feb. 05, 2009
Applicants:

James Francis Callahan, King of Prussia, PA (US);

Guoliang Lin, King of Prussia, PA (US);

Zehong Wan, Shanghai, CN;

Hongxing Yan, King of Prussia, PA (US);

Inventors:

James Francis Callahan, King of Prussia, PA (US);

Guoliang Lin, King of Prussia, PA (US);

Zehong Wan, Shanghai, CN;

Hongxing Yan, King of Prussia, PA (US);

Assignee:

Glaxo Group Limited, Greenford, Middlesex, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/551 (2006.01); A61K 31/437 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.


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