The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
May. 26, 2006
Yasuo Suda, Kagoshima, JP;
Tomoaki Nishimura, Hyogo, JP;
Yuko Kishimoto, Hyogo, JP;
Hiromi Nakagawa, Shizuoka, JP;
Yasuo Suda, Kagoshima, JP;
Tomoaki Nishimura, Hyogo, JP;
Yuko Kishimoto, Hyogo, JP;
Hiromi Nakagawa, Shizuoka, JP;
Japan Science and Technology Agency, Saitama, JP;
National University Corporation Kagoshima University, Kagoshima, JP;
Abstract
It is intended to provide a stable novel sugar-immobilized metal nanoparticle capable of easily immobilizing a sugar chain, a method for measuring sugar-protein interaction easily and at a low cost using the same without labeling, and a method for simply recovering a protein from a sugar-protein interactant. A maltose-immobilized gold nanoparticle was obtained by binding a ligand complex, in which maltose and a linker compound had been bound to each other, to a gold nanoparticle. By adding this maltose-immobilized gold nanoparticle to a dilution series of concanavalin A, a sugar-protein interactant of maltose and ConA was formed, and red-purple color derived from a colloidal solution of maltose-immobilized gold nanoparticle disappeared. That is, sugar-protein interaction could be confirmed by visual observation without labeling.