The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
Oct. 10, 2003
Applicants:
Reinhard Wähler, Hamburg, DE;
Frank Schnieders, Hamburg, DE;
Inventors:
Reinhard Wähler, Hamburg, DE;
Frank Schnieders, Hamburg, DE;
Assignee:
Universitätsklinikum Hamburg-Eppendorf, Hamburg, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to viral vectors comprising nucleic acid sequences coding for single chain interleukin-12 (single chain IL-12 or scIL12) and a costimulator protein, and to the use of vectors for gene therapy, especially for the treatment of tumors. The invention further relates to adenoviral vectors containing nucleic acid sequences having a sequence homology of at least 90% in relation to the sequence displayed in FIGS.and(IL-12), in FIG.(4-1BB ligand) and in FIG.(IL-2) and optionally also one of the sequences displayed in FIG.A (B7-1) orB (B7-2).