The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
May. 30, 2007
Applicants:
Hyun Jin Hwang, Seoul, KR;
Jeong Hee Kim, Seoul, KR;
Inventors:
Hyun Jin Hwang, Seoul, KR;
Jeong Hee Kim, Seoul, KR;
Assignee:
Ahram Biosystems Inc., Seoul, KR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 11/02 (2006.01); C12N 11/10 (2006.01); C12N 11/08 (2006.01); C12N 11/06 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a DNA polymerase immobilized by covalent bonding. More particularly, the present invention relates to an immobilized DNA polymerase whose activity is maximally preserved by masking the active site of the DNA polymerase and optimizing interaction of the masked molecule to the substrate material. In one embodiment, the average activity of the immobilized DNA polymerase is more than about 10% relative to that of the solution phase DNA polymerase. Further provided by the invention are methods and kits for performing polymerase chain reactions (PCR).