The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2011
Filed:
Jul. 19, 2006
Applicants:
Stephen D. Gillies, Carlisle, MA (US);
Jeffrey Way, Cambridge, MA (US);
Kin-ming Lo, Lexington, MA (US);
Inventors:
Stephen D. Gillies, Carlisle, MA (US);
Jeffrey Way, Cambridge, MA (US);
Kin-Ming Lo, Lexington, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07H 21/04 (2006.01); C12N 5/07 (2010.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are methods and compositions for efficiently expressing antibody fusion proteins. Antibody fusion proteins of the invention include a hybrid antibody moiety containing sequences from more than one type of antibody and/or mutant antibody sequences. Hybrid antibody fusion proteins of the invention may be produced at high levels and may combine functional properties characteristic of different antibody types in addition to functional properties of a non-antibody moiety.