The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2011

Filed:

Aug. 27, 2008
Applicants:

Mingshi Dai, Lexington, MA (US);

Bing Guan, Needham, MA (US);

Robert A. Bennett, Milford, MA (US);

Douglas F. Burdi, Arlington, MA (US);

Shomir Ghosh, Brookline, MA (US);

Gang LI, Westborough, MA (US);

Charles A. Minor, Kingston, MA (US);

Tracy J. Jenkins, Belmont, MA (US);

Inventors:

Mingshi Dai, Lexington, MA (US);

Bing Guan, Needham, MA (US);

Robert A. Bennett, Milford, MA (US);

Douglas F. Burdi, Arlington, MA (US);

Shomir Ghosh, Brookline, MA (US);

Gang Li, Westborough, MA (US);

Charles A. Minor, Kingston, MA (US);

Tracy J. Jenkins, Belmont, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R, X, Z, R, X, Ar, n, Rand Rare defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.


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