The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2011
Filed:
Dec. 11, 2007
Harold Burns Brooks, Carmel, IN (US);
Joyce Z. Crich, Indianapolis, IN (US);
James Robert Henry, Indianapolis, IN (US);
Hong-yu LI, Zionsville, IN (US);
Jason Scott Sawyer, Indianapolis, IN (US);
Yan Wang, Carmel, IN (US);
Harold Burns Brooks, Carmel, IN (US);
Joyce Z. Crich, Indianapolis, IN (US);
James Robert Henry, Indianapolis, IN (US);
Hong-Yu Li, Zionsville, IN (US);
Jason Scott Sawyer, Indianapolis, IN (US);
Yan Wang, Carmel, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. Formula I wherein: Ris aminomethyl, (C-Calkyl)aminomethyl, di(C-Calkyl)aminomethyl, N-ethyl-N-methyl-aminomethyl, 1-aminoethyl, 1-((C-Calkyl)amino)-ethyl, 3,3,3-trifluoro-propylaminomethyl, ethynyl, 2-hydroxy-ethoxy, 2-hydroxyethylaminomethyl, 2-cyanoethylaminomethyl, morpholin-4-ylmethyl, methoxymethoxymethyl, cyclopropyl, 1-azetidinylmethyl, 1-pyrrolidinylmethyl, or 1,3-dioxolan-2-yl; Ris hydrogen or halo; Ris hydrogen or halo; provided that at least one of Rand Ris hydrogen; Ris hydrogen, methyl, or halo; and is a single bond that is either present or absent, or pharmaceutically acceptable salt thereof.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile