The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2011
Filed:
Apr. 16, 2009
Zhaozhong J. Jia, San Mateo, CA (US);
Chandrasekar Venkataramani, Redwood City, CA (US);
Wolin Huang, Foster City, CA (US);
Mukund Mehrotra, South San Francisco, CA (US);
Yonghong Song, Foster City, CA (US);
Qing Xu, Foster City, CA (US);
Shawn M. Bauer, Pacifica, CA (US);
Jack W. Rose, San Mateo, CA (US);
Brian Kane, Pleasant Hill, CA (US);
Anjali Pandey, Fremont, CA (US);
Zhaozhong J. Jia, San Mateo, CA (US);
Chandrasekar Venkataramani, Redwood City, CA (US);
Wolin Huang, Foster City, CA (US);
Mukund Mehrotra, South San Francisco, CA (US);
Yonghong Song, Foster City, CA (US);
Qing Xu, Foster City, CA (US);
Shawn M. Bauer, Pacifica, CA (US);
Jack W. Rose, San Mateo, CA (US);
Brian Kane, Pleasant Hill, CA (US);
Anjali Pandey, Fremont, CA (US);
Portola Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.