The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2011
Filed:
Feb. 23, 2010
Essa HU, Camarillo, CA (US);
Jason Brooks Human, Boston, MA (US);
Roxanne Kunz, Santa Monica, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Ryan White, Somerville, MA (US);
Essa Hu, Camarillo, CA (US);
Jason Brooks Human, Boston, MA (US);
Roxanne Kunz, Santa Monica, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Ryan White, Somerville, MA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various inflammatory, fibrotic and/or mast cell mediated diseases such as mastocytosis. The compounds have a general Formula I wherein Aand Rare defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.