The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2011

Filed:

Jul. 05, 2007
Applicants:

Ian S. Mitchell, Lafayette, CO (US);

James F. Blake, Longmont, CO (US);

Rui Xu, Longmont, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Dengming Xiao, Longmont, CO (US);

Keith Lee Spencer, Lyons, CO (US);

Josef R. Bencsik, Longmont, CO (US);

Eli M. Wallace, Lyons, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Anna L. Banka, Longmont, CO (US);

Jun Liang, Palo Alto, CA (US);

Brian Safina, Redwood City, CA (US);

Birong Zhang, Union City, CA (US);

Christine Chabot, San Mateo, CA (US);

Steven DO, San Jose, CA (US);

Inventors:

Ian S. Mitchell, Lafayette, CO (US);

James F. Blake, Longmont, CO (US);

Rui Xu, Longmont, CO (US);

Nicholas C. Kallan, Boulder, CO (US);

Dengming Xiao, Longmont, CO (US);

Keith Lee Spencer, Lyons, CO (US);

Josef R. Bencsik, Longmont, CO (US);

Eli M. Wallace, Lyons, CO (US);

Stephen T. Schlachter, Boulder, CO (US);

Anna L. Banka, Longmont, CO (US);

Jun Liang, Palo Alto, CA (US);

Brian Safina, Redwood City, CA (US);

Birong Zhang, Union City, CA (US);

Christine Chabot, San Mateo, CA (US);

Steven Do, San Jose, CA (US);

Assignees:

Array BioPharma Inc., Boulder, CO (US);

Covenentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/70 (2006.01); A61K 31/496 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.


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