The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2011
Filed:
Mar. 23, 2010
Hiroshi Koyano, Kamakura, JP;
Atsushi Suda, Kamakura, JP;
Kousuke Aso, Kamakura, JP;
Kihito Hada, Kamakura, JP;
Miyuki Asai, Kamakura, JP;
Masami Hasegawa, Kamakura, JP;
Yasuko Sato, Kamakura, JP;
Hiroshi Koyano, Kamakura, JP;
Atsushi Suda, Kamakura, JP;
Kousuke Aso, Kamakura, JP;
Kihito Hada, Kamakura, JP;
Miyuki Asai, Kamakura, JP;
Masami Hasegawa, Kamakura, JP;
Yasuko Sato, Kamakura, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
Compounds having high angiogenesis inhibiting activity useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, e.g. cancer and cancer metastasis, are of formula (II), where Ais C—Xor N; Qis -A=A-, or a heteroatom selected from —O—, —S—, and —N(R)—; Qis -A=A-, or a heteroatom selected from —O—, —S—, and —N(R)—; provided that Qand Qare not heteroatoms at the same time; Ais C—Xor N, Ais C—Xor N, Ais C—Xor N, and Ais C—Xor N; Y is Calkyl, Ccycloalkyl, Calkenyl, Calkynyl, Calkoxy, Calkenyloxy, Calkynyloxy, or Calkylthio; Z is a hydrogen atom, hydroxy, Calkyl, Ccycloalkyl, or —NRR; and L is selected from the formula: