The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2011
Filed:
Sep. 29, 2000
Hiroyuki Saito, Gotenba, JP;
Takehisa Kitazawa, Gotenba, JP;
Kazutaka Yoshihashi, Gotenba, JP;
Kunihiro Hattori, Gotenba, JP;
Hiroyuki Saito, Gotenba, JP;
Takehisa Kitazawa, Gotenba, JP;
Kazutaka Yoshihashi, Gotenba, JP;
Kunihiro Hattori, Gotenba, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
Provided herein is an animal having a persistent hypercoagulable state by implanting a cell, for example a tumor cell, in which the gene of human tissue factor is implanted to an experimental animal such as a mouse and then growing the cell, thereby persistently supplying human tissue factor to the experimental animal. This animal model is useful for research and development of therapeutic agents for diseases having a persistent hypercoagulable state. Also provided are preventive or therapeutic agents for diseases having a persistent hypercoagulable state, a hypercoagulable state resulting from infections, venous thrombosis, arterial thrombosis, and diseases resulting from the hypertrophy of vascular media, the agent comprising an antibody against human tissue factor (human TF) as an active ingredient.