The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2011
Filed:
Jun. 25, 2007
Akihiro Ishii, Saitama, JP;
Takashi Ootsuka, Fujimino, JP;
Manabu Yasumoto, Fujimino, JP;
Hideyuki Tsuruta, Fujimino, JP;
Kenjin Inomiya, Fujimino, JP;
Koji Ueda, Fujimino, JP;
Kaori Mogi, Fujimino, JP;
Akihiro Ishii, Saitama, JP;
Takashi Ootsuka, Fujimino, JP;
Manabu Yasumoto, Fujimino, JP;
Hideyuki Tsuruta, Fujimino, JP;
Kenjin Inomiya, Fujimino, JP;
Koji Ueda, Fujimino, JP;
Kaori Mogi, Fujimino, JP;
Central Glass Company, Limited, Ube-shi, JP;
Abstract
There is provided a novel, useful dehydroxyfluorination agent containing sulfuryl fluoride (SOF) and an organic base that is free from a free hydroxyl group in the molecule. According to the present dehydroxyfluorination agent, it is not necessary to use perfluoroalkanesulfonyl fluoride, which is not preferable in large-scale use, and it is possible to advantageously produce optically-active fluoro derivatives, which are important intermediates of medicines, agricultural chemicals and optical materials, for example, 4-fluoroproline derivatives, 2'-deoxy-2′-fluorouridine derivatives, optically-active α-fluorocarboxylate derivatives, and monofluoromethyl derivatives, even in large scale.