The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2011
Filed:
Apr. 12, 2010
Applicants:
Masakazu Sugiyama, Kawasaki, JP;
Kunihiko Watanabe, Kawasaki, JP;
Tatsuki Kashiwagi, Kawasaki, JP;
Ei-ichiro Suzuki, Kawasaki, JP;
Inventors:
Masakazu Sugiyama, Kawasaki, JP;
Kunihiko Watanabe, Kawasaki, JP;
Tatsuki Kashiwagi, Kawasaki, JP;
Ei-ichiro Suzuki, Kawasaki, JP;
Assignee:
Ajinomoto Co., Inc., Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 13/04 (2006.01); C12P 17/10 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
A D-aminotransferase can be modified so as to efficiently produce (2R,4R)-monatin having high sweetness intensity from 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid by substituting an amino acid at least at one of positions (positions 100, 180 to 183, 243 and 244) involved in efficiently producing the (2R,4R)-monatin in an amino acid sequence of a wild-type D-aminotransferase represented in SEQ ID NO:2.