The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2011
Filed:
Dec. 21, 2006
Liming Shao, Lincoln, MA (US);
Fengjiang Wang, Northborough, MA (US);
Scott Christopher Malcolm, Southborough, MA (US);
Michael Charles Hewitt, Somerville, MA (US);
Larry R. Bush, Worcester, MA (US);
Mark A. Varney, Laguna Niguel, CA (US);
Una Campbell, Marlborough, MA (US);
Sharon Rae Engel, Hudson, MA (US);
Larry Wendell Hardy, Sturbridge, MA (US);
Patrick Koch, Marlborough, MA (US);
Jianguo MA, Natick, MA (US);
Liming Shao, Lincoln, MA (US);
Fengjiang Wang, Northborough, MA (US);
Scott Christopher Malcolm, Southborough, MA (US);
Michael Charles Hewitt, Somerville, MA (US);
Larry R. Bush, Worcester, MA (US);
Mark A. Varney, Laguna Niguel, CA (US);
Una Campbell, Marlborough, MA (US);
Sharon Rae Engel, Hudson, MA (US);
Larry Wendell Hardy, Sturbridge, MA (US);
Patrick Koch, Marlborough, MA (US);
Jianguo Ma, Natick, MA (US);
Sunovion Pharmaceuticals Inc., Marlborough, MA (US);
Abstract
The invention relates to novel tetralone based amines and their use in the treatment of central nervous system (CNS) disorders, such as depression, attention deficit hyperactivity disorder (ADHD) and Parkinson's disease. The invention further relates to pharmaceutical compositions containing the compounds and compositions of the invention as well as methods of inhibiting reuptake of one or more monoamine, such as such as dopamine and norepinephrine, from the synaptic cleft, and methods of modulating one or more monoamine transporter.