The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2011

Filed:

Aug. 15, 2006
Applicants:

Song LI, Beijing, CN;

Changbin Guo, Beijing, CN;

Xiancheng Jiang, Beijing, CN;

Junhai Xiao, Beijing, CN;

Zhong Wu, Beijing, CN;

Inventors:

Song Li, Beijing, CN;

Changbin Guo, Beijing, CN;

Xiancheng Jiang, Beijing, CN;

Junhai Xiao, Beijing, CN;

Zhong Wu, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 277/44 (2006.01); A61K 31/425 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to 2,4,5-trisubstituted thiazole compounds of formula (I) or all possible isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof for the inhibition of plasma PLTP activity and/or plasma CETP activity, wherein the substituents are as defined in the specification; a process for the preparation of the compounds of formula (I); a pharmaceutical composition comprising the compound of formula (I) and its use for the preparation of a medicament for treatment and/or prevention of diseases associated with the increased plasma PLTP activity and/or the increased plasma CETP activity in a mammal, such as atherosclerosis, cardiovascular diseases and peripheral vascular diseases, etc.


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