The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2011

Filed:

Nov. 23, 2005
Applicants:

David Hone, Rockville, MD (US);

John Fulkerson, Silver Spring, MD (US);

Jerald C. Sadoff, Washington, DC (US);

David Onyabe, Poolesville, MD (US);

Michele Stone, Ellicott City, MD (US);

Inventors:

David Hone, Rockville, MD (US);

John Fulkerson, Silver Spring, MD (US);

Jerald C. Sadoff, Washington, DC (US);

David Onyabe, Poolesville, MD (US);

Michele Stone, Ellicott City, MD (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/04 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Bacterial packaging strains useful for generating recombinant double-stranded RNA nucleocapsids (rdsRNs) are provided. The packaging strains are useful for the production of RNA encoding vaccine antigens, bioactive proteins, immunoregulatory proteins, antisense RNAs, and catalytic RNAs in eukaryotic cells or tissues. Recombinant ssRNA is introduced into the strains and packaged to form rdsRNs de novo.


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