The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2011
Filed:
Mar. 27, 2003
Applicants:
David J. Weber, Towson, MD (US);
Joseph Markowitz, Baltimore, MD (US);
France Carrier, Silver Spring, MD (US);
Alexander D. Mackerell, Baltimore, MD (US);
Inventors:
David J. Weber, Towson, MD (US);
Joseph Markowitz, Baltimore, MD (US);
France Carrier, Silver Spring, MD (US);
Alexander D. MacKerell, Baltimore, MD (US);
Assignee:
University of Maryland, Baltimore, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/52 (2006.01); A01N 31/14 (2006.01); A61K 31/155 (2006.01); A61K 31/075 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds that bind S100 and inhibit the S100-p53 protein-protein interaction and activate the tumor suppressor activity of p53, and thus which have an antineoplastic effect are disclosed, as well as methods for identifying these compounds, compositions comprising the same, and methods of using the same to treat cancer.