The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Dec. 18, 2007
Joerg Bruening, Wilmington, DE (US);
Gary David Annis, Landenberg, PA (US);
Donald J Dumas, Wilmington, DE (US);
Rafael Shapiro, Wilmington, DE (US);
Joerg Bruening, Wilmington, DE (US);
Gary David Annis, Landenberg, PA (US);
Donald J Dumas, Wilmington, DE (US);
Rafael Shapiro, Wilmington, DE (US);
E. I. du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 wherein Ris NHRor OR; Ris CHor Cl; Ris H, C-Calkyl, cyclopropyl, cyclopropylcyclopropyl, cyclopropylmethyl or methylcyclopropyl; Ris H or C-Calkyl; Y is Br or Cl; X is NRor O; n is 0 or 1; and R, R, R, R, R, R, R, Rand Rare as defined in the disclosure. Also disclosed is a method for preparing a compound of Formula 2 wherein Y is Br and Ris NHRcomprising introducing a gas containing bromine into a liquid containing a compound of Formula 4, and further disclosed is a method for preparing a compound of Formula 5 wherein R, R, Rand Z are as defined in the disclosure using a compound of Formula 1 characterized by preparing the compound of Formula 1 by the method disclosed above.