The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Oct. 20, 2008
Applicants:
Erkki Ruoslahti, Rancho Santa Fe, CA (US);
Kimmo Porkka, Helsinki, FI;
Sven Christian, San Diego, CA (US);
Inventors:
Erkki Ruoslahti, Rancho Santa Fe, CA (US);
Kimmo Porkka, Helsinki, FI;
Sven Christian, San Diego, CA (US);
Assignee:
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/00 (2006.01); C07K 14/00 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided.